Management of Tooth with Periapical Lesion and Severe External and Internal Root Resorption - 5 year Follow-Up - Two Case Reports

One of the main principles of endodontic treatment is the three-dimensional root canal filling, with a focus on filling the apical third of the root. The management of cases with periapical lesion and severe resorption internal and external, still remains a clinical challenge. Biological approaches of tissue engineering will yield new diagnostic and therapeutic way to repair soft tissue as well as bone structure.Nanosize biphasic calcium phosphate materials play a significant role in various biomedical applications, due to its unique fictional properties, high surface area to volume ratio and its ultra-fine structure, similar to that of the biological bone apatite. These promising materials find a place in contemporary treatment of cases with extremely areas of resorption.